| Gene Information | |
|---|---|
| Gene Name | AGPAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 278 |
| Protein Names | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 2) (1-AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase beta) (LPAAT-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000169692 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O15120 |
| Gene Card | AGPAT2 |
| Uniprot ID | O15120 |
| Pfam | PF01553 |
| In ASD | no |
| Allosteric Prediction | no (-0.103036203) |
| Ortholog in Animals | Alpaca_ AGPAT2 ( ortholog_one2one ) Dog_ AGPAT2 ( ortholog_one2one ) GuineaPig_ AGPAT2 ( ortholog_one2one ) Macaque_ AGPAT2 ( ortholog_one2one ) Mouse_ Agpat2 ( ortholog_one2one ) Pig_ AGPAT2 ( ortholog_one2many ) Rat_ Agpat2 ( ortholog_one2one ) |
| Ohnologs | AGPAT1 |
| Paralogs | AGPAT1 |
| Tissue | breast, pancreas |
| Tissue Specificity | Expressed predominantly in adipose tissue, pancreas and liver. {ECO:0000269|PubMed:21873652, ECO:0000269|PubMed:9242711}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs797045222 rs104894100 rs145975461 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21873652}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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