| Gene Information | |
|---|---|
| Gene Name | AGO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 857 |
| Protein Names | Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000092847 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UL18 |
| Gene Card | AGO1 |
| Uniprot ID | Q9UL18 |
| Pfam | PF08699; PF16488; PF16487; PF16486; PF02170; PF02171 |
| In ASD | no |
| Allosteric Prediction | yes (0.848546072) |
| Ortholog in Animals | Alpaca_ AGO1 ( ortholog_one2one ) Dog_ AGO1 ( ortholog_one2one ) GuineaPig_ AGO1 ( ortholog_one2one ) Macaque_ AGO1 ( ortholog_one2one ) Mouse_ Ago1 ( ortholog_one2one ) Rat_ Ago1 ( ortholog_one2one ) Rabbit_ AGO1 ( ortholog_one2one ) |
| Ohnologs | AGO2 |
| Paralogs | AGO4, AGO3, AGO2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.008511(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SI2 (X-ray 2.60A ) 1SI3 (X-ray 2.60A ) 4KRE (X-ray 1.75A ) 4KRF (X-ray 2.10A ) 4KXT (X-ray 2.29A ) 5W6V (X-ray 2.83A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:20616046}. |
| Mouse PG classification | NA |
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