| Gene Information | |
|---|---|
| Gene Name | AGBL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 503 |
| Protein Names | Cytosolic carboxypeptidase 6 (EC 3.4.17.24) (ATP/GTP-binding protein-like 4) (Protein deglutamylase CCP6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000186094 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q5VU57 |
| Gene Card | AGBL4 |
| Uniprot ID | Q5VU57 |
| Pfam | PF18027; PF00246 |
| In ASD | no |
| Allosteric Prediction | no (-1.30283882) |
| Ortholog in Animals | Alpaca_ AGBL4 ( ortholog_one2one ) GuineaPig_ AGBL4 ( ortholog_one2one ) Macaque_ AGBL4 ( ortholog_one2one ) Mouse_ Agbl4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AGBL3, AGTPBP1, AGBL5, AGBL1, AGBL2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs60977321 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09LZ8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23085998}. Golgi apparatus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23085998}. Note=Colocalizes with gamma-tubulin in the centrioles at interphase and dividing cells and with glutamylated tubulin in basal bodies of ciliated cells. {ECO:0000269|PubMed:23085998}. |
| Mouse PG classification | NA |
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