| Gene Information | |
|---|---|
| Gene Name | AFM |
| Organism | Homo sapiens (Human) |
| Gene Length | 599 |
| Protein Names | Afamin (Alpha-albumin) (Alpha-Alb) |
| Target Name | afamin |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000079557 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P43652 |
| Gene Card | AFM |
| Uniprot ID | P43652 |
| Pfam | PF00273 |
| In ASD | no |
| Allosteric Prediction | no (-0.688664824) |
| Ortholog in Animals | Alpaca_ AFM ( ortholog_one2one ) Dog_ AFM ( ortholog_one2one ) GuineaPig_ AFM ( ortholog_one2one ) Macaque_ AFM ( ortholog_one2one ) Mouse_ Afm ( ortholog_one2one ) Pig_ AFM ( ortholog_one2one ) Rat_ Afm ( ortholog_one2one ) Rabbit_ AFM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AFP, ALB, GC |
| Tissue | liver |
| Tissue Specificity | High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:7517938}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5OKL (X-ray 2.09A ) 6FAK (X-ray 1.90A ) 6RQ7 (X-ray 2.69A ) |
| DBSNP | rs41265665 rs2276444 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:26902720, ECO:0000269|PubMed:7517938}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |