| Gene Information | |
|---|---|
| Gene Name | CYP2R1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 501 |
| Protein Names | Vitamin D 25-hydroxylase (EC 1.14.14.24) (Cytochrome P450 2R1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000186104 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6VVX0 |
| Gene Card | CYP2R1 |
| Uniprot ID | Q6VVX0 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-0.153499941) |
| Ortholog in Animals | Alpaca_ CYP2R1 ( ortholog_one2one ) Dog_ CYP2R1 ( ortholog_one2many ) GuineaPig_ CYP2R1 ( ortholog_one2one ) Macaque_ CYP2R1 ( ortholog_one2one ) Mouse_ Cyp2r1 ( ortholog_one2one ) Pig_ CYP2R1 ( ortholog_one2one ) Rat_ Cyp2r1 ( ortholog_one2one ) Rabbit_ CYP2R1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CYP2S1, CYP2W1, CYP2D6, CYP2C18, CYP2C9, CYP2C19, CYP2B6, CYP2C8, CYP2U1, CYP2A6, CYP2A7, CYP2A13, CYP2F1, CYP2E1, CYP2J2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3C6G (X-ray 2.80A ) 3CZH (X-ray 2.30A ) 3DL9 (X-ray 2.72A ) |
| DBSNP | rs61495246 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305|PubMed:15465040}; Peripheral membrane protein. Microsome membrane {ECO:0000305|PubMed:15465040}; Peripheral membrane protein. |
| Mouse PG classification | NA |
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