Gene Information
Gene NameAFF1
OrganismHomo sapiens (Human)
Gene Length1210
Protein NamesAF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000172493 )
Evolutionary StageVertebrata
AlphaFoldDBP51825
Gene CardAFF1
Uniprot IDP51825
PfamPF18876; PF18875
In ASDno
Allosteric Predictionno (-0.031965197)
Ortholog in AnimalsAlpaca_ AFF1 ( ortholog_one2one )
Dog_ AFF1 ( ortholog_one2one )
GuineaPig_ AFF1 ( ortholog_one2one )
Macaque_ AFF1 ( ortholog_one2one )
Mouse_ Aff1 ( ortholog_one2one )
Pig_ AFF1 ( ortholog_one2one )
Rat_ Aff1 ( ortholog_one2one )
Rabbit_ AFF1 ( ortholog_one2one )
OhnologsAFF4, AFF2, AFF3
ParalogsAFF3, AFF4, AFF2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001899(Rat);0.018182(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2LM0  (NMR 
DBSNP rs3733378 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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