| Gene Information | |
|---|---|
| Gene Name | CAMK2N2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 79 |
| Protein Names | Calcium/calmodulin-dependent protein kinase II inhibitor 2 (CaM-KII inhibitory protein) (CaM-KIIN) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163888 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96S95 |
| Gene Card | CAMK2N2 |
| Uniprot ID | Q96S95 |
| Pfam | PF15170 |
| In ASD | no |
| Allosteric Prediction | no (-1.471267016) |
| Ortholog in Animals | Alpaca_ CAMK2N2 ( ortholog_one2one ) Dog_ CAMK2N2 ( ortholog_one2one ) Macaque_ CAMK2N2 ( ortholog_one2one ) Mouse_ Camk2n2 ( ortholog_one2one ) Pig_ CAMK2N2 ( ortholog_one2one ) Rabbit_ CAMK2N2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CAMK2N1 |
| Tissue | adrenal.gland, brain, pancreas |
| Tissue Specificity | Highly Expressed in keyhole limpet hemocyanin-stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC (PubMed:11444830). Highly expressed in kidney and liver (PubMed:11444830). Moderately expressed in heart, skeletal muscle, and placenta (PubMed:11444830). Weakly expressed in the small intestine (PubMed:11444830). {ECO:0000269|PubMed:11444830}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q9Z2N6}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Z2N6}. Synapse {ECO:0000250|UniProtKB:Q78WH7}. Note=Excluded from nucleus when coexpressed with activated CAMK2. {ECO:0000250|UniProtKB:Q9Z2N6}. |
| Mouse PG classification | NA |
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