| Gene Information | |
|---|---|
| Gene Name | ADSS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 457 |
| Protein Names | Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (Adenylosuccinate synthetase-like 1) (AdSSL1) (IMP--aspartate ligase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000185100 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8N142 |
| Gene Card | ADSS1 |
| Uniprot ID | Q8N142 |
| Pfam | PF00709 |
| In ASD | no |
| Allosteric Prediction | yes (0.329588297) |
| Ortholog in Animals | Alpaca_ ADSS1 ( ortholog_one2one ) Dog_ ADSS1 ( ortholog_one2one ) GuineaPig_ ADSS1 ( ortholog_one2one ) Macaque_ ADSS1 ( ortholog_one2one ) Mouse_ Adssl1 ( ortholog_one2one ) Pig_ ADSS1 ( ortholog_one2one ) Rat_ Adssl1 ( ortholog_one2one ) Rabbit_ ADSS1 ( ortholog_one2one ) |
| Ohnologs | ADSS2 |
| Paralogs | ADSS2 |
| Tissue | skeletal.muscle, heart, testis |
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors. {ECO:0000269|PubMed:15786719}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033382(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs140614802 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03126, ECO:0000269|PubMed:15786719}. |
| Mouse PG classification | NA |
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