| Gene Information | |
|---|---|
| Gene Name | MPPE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000154889 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q53F39 |
| Gene Card | MPPE1 |
| Uniprot ID | Q53F39 |
| Pfam | PF00149 |
| In ASD | no |
| Allosteric Prediction | no (-1.56823463) |
| Ortholog in Animals | Alpaca_ MPPE1 ( ortholog_one2one ) GuineaPig_ MPPE1 ( ortholog_one2one ) Macaque_ MPPE1 ( ortholog_one2one ) Mouse_ Mppe1 ( ortholog_one2one ) Pig_ MPPE1 ( ortholog_one2one ) Rat_ Mppe1 ( ortholog_one2one ) Rabbit_ MPPE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. {ECO:0000269|PubMed:11978971}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.175650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11872520 rs35611363 rs662515 rs16976814 |
| Subcellular location [CC] | Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19837036}; Multi-pass membrane protein {ECO:0000269|PubMed:19837036}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19837036}; Multi-pass membrane protein {ECO:0000269|PubMed:19837036}. Note=Also localizes to endoplasmic reticulum exit site. |
| Mouse PG classification | NA |
| click here to return to the previous page | |