| Gene Information | |
|---|---|
| Gene Name | ADORA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | Adenosine receptor A3 |
| Target Name | adenosine a3 receptor |
| Target Type | Clinical trial target |
| Gene Age | 3 ( ENSG00000282608 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P0DMS8 |
| Gene Card | ADORA3 |
| Uniprot ID | P0DMS8 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.474475215) |
| Ortholog in Animals | Dog_ ADORA3 ( ortholog_one2one ) GuineaPig_ ADORA3 ( ortholog_one2one ) Mouse_ Adora3 ( ortholog_one2one ) Rat_ Adora3 ( ortholog_one2one ) Rabbit_ ADORA3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADORA1, ADORA2A, ADORA2B |
| Tissue | NA |
| Tissue Specificity | Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level). {ECO:0000269|PubMed:27886186}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs746154553 rs35511654 rs2800889 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q28309}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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