Gene Information
Gene NameADNP
OrganismHomo sapiens (Human)
Gene Length1102
Protein NamesActivity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000101126 )
Evolutionary StageVertebrata
AlphaFoldDBQ9H2P0
Gene CardADNP
Uniprot IDQ9H2P0
PfamPF19627; PF00046
In ASDno
Allosteric Predictionno (-0.088037224)
Ortholog in AnimalsAlpaca_ ADNP ( ortholog_one2one )
Dog_ ADNP ( ortholog_one2one )
GuineaPig_ ADNP ( ortholog_one2one )
Macaque_ ADNP ( ortholog_one2one )
Mouse_ Adnp ( ortholog_one2one )
Pig_ ADNP ( ortholog_one2one )
Rat_ Adnp ( ortholog_one2one )
Rabbit_ ADNP ( ortholog_one2one )
OhnologsNA
ParalogsADNP2
TissueNA
Tissue SpecificityWidely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs780706686 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. Chromosome {ECO:0000250|UniProtKB:Q9Z103}.
Mouse PG classificationNA
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