Gene Information
Gene NameADIPOR2
OrganismHomo sapiens (Human)
Gene Length386
Protein NamesAdiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II)
Target NameNA
Target TypeNA
Gene Age810 ( ENSG00000006831 )
3 ( ENSG00000285070 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ86V24
Gene CardADIPOR2
Uniprot IDQ86V24
PfamPF03006
In ASDno
Allosteric Predictionno (-0.084374341)
Ortholog in AnimalsAlpaca_ ADIPOR2 ( ortholog_one2one )
Dog_ ADIPOR2 ( ortholog_one2one )
GuineaPig_ ADIPOR2 ( ortholog_one2one )
Macaque_ ADIPOR2 ( ortholog_one2one )
Mouse_ Adipor2 ( ortholog_one2one )
Pig_ ADIPOR2 ( ortholog_one2one )
Rat_ Adipor2 ( ortholog_one2one )
Rabbit_ ADIPOR2 ( ortholog_one2one )
OhnologsADIPOR1
ParalogsPAQR6, PAQR8, PAQR9, MMD2, PAQR3, MMD, PAQR7, PAQR5, PAQR4, ADIPOR1
Tissuesubstantia.nigra
Tissue SpecificityUbiquitous (PubMed:16044242). Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337). Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:12802337). {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:16044242}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5LWY  (X-ray  2.40A  )  5LX9  (X-ray  2.40A  )  5LXA  (X-ray  3.00A  )  6KS1  (X-ray  2.40A  )  6YX9  (X-ray  2.40A  )  6YXD  (X-ray  2.90A  )  6YXF  (X-ray  3.02A  )  6YXG  (X-ray  3.01A  ) 
DBSNP rs12298275 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:25855295};
Multi-pass membrane protein {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:25855295}. Note=Localized to the cell membrane and intracellular organelles. {ECO:0000269|PubMed:12802337}.
Mouse PG classificationNA
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