| Gene Information | |
|---|---|
| Gene Name | ADHFE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 467 |
| Protein Names | Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000147576 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8IWW8 |
| Gene Card | ADHFE1 |
| Uniprot ID | Q8IWW8 |
| Pfam | PF00465 |
| In ASD | no |
| Allosteric Prediction | no (-0.055149007) |
| Ortholog in Animals | Alpaca_ ADHFE1 ( ortholog_one2one ) Dog_ VXN ( ortholog_one2one ) GuineaPig_ ADHFE1 ( ortholog_one2one ) Macaque_ ADHFE1 ( ortholog_one2one ) Mouse_ Adhfe1 ( ortholog_one2one ) Pig_ ADHFE1 ( ortholog_one2one ) Rat_ Adhfe1 ( ortholog_one2one ) Rabbit_ ADHFE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Only expressed in adult liver. {ECO:0000269|PubMed:12592711}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.008533(Rat);0.067723(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1060242 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250}. |
| Mouse PG classification | NA |
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