| Gene Information | |
|---|---|
| Gene Name | ADH4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | All-trans-retinol dehydrogenase [NAD(+)] ADH4 (EC 1.1.1.105) (Alcohol dehydrogenase 4) (Alcohol dehydrogenase class II pi chain) |
| Target Name | alcohol dehydrogenase 4 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000198099 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P08319 |
| Gene Card | ADH4 |
| Uniprot ID | P08319 |
| Pfam | PF08240; PF00107 |
| In ASD | no |
| Allosteric Prediction | no (-0.154387204) |
| Ortholog in Animals | Alpaca_ ADH4 ( ortholog_one2one ) Dog_ ADH4 ( ortholog_one2one ) Macaque_ ADH4 ( ortholog_one2one ) Mouse_ Adh4 ( ortholog_one2one ) Pig_ ADH4 ( ortholog_one2one ) Rabbit_ ADH4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MECR, CRYZ, RTN4IP1, PTGR2, TP53I3, CRYZL1, PTGR3, ADH6, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH5, ADH7, VAT1 |
| Tissue | liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3COS (X-ray 2.10A ) |
| DBSNP | rs1126671 rs29001219 rs1126673 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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