Gene Information
Gene NameTFCP2L1
OrganismHomo sapiens (Human)
Gene Length479
Protein NamesTranscription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000115112 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ9NZI6
Gene CardTFCP2L1
Uniprot IDQ9NZI6
PfamPF04516; PF18016
In ASDno
Allosteric Predictionno (-1.133849463)
Ortholog in AnimalsAlpaca_ TFCP2L1 ( ortholog_one2one )
Dog_ TFCP2L1 ( ortholog_one2one )
GuineaPig_ TFCP2L1 ( ortholog_one2one )
Macaque_ TFCP2L1 ( ortholog_one2one )
Mouse_ Tfcp2l1 ( ortholog_one2one )
Pig_ TFCP2L1 ( ortholog_one2one )
Rat_ Tfcp2l1 ( ortholog_one2one )
Rabbit_ TFCP2L1 ( ortholog_one2one )
OhnologsTFCP2, UBP1
ParalogsGRHL1, GRHL3, GRHL2, UBP1, TFCP2
Tissuecortex.of.kidney, minor.salivary.gland, thyroid
Tissue SpecificityHighly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue. {ECO:0000269|PubMed:10644752}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:10644752}.
Mouse PG classificationNA
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