| Gene Information | |
|---|---|
| Gene Name | ADGRG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 549 |
| Protein Names | Adhesion G protein-coupled receptor G3 (G-protein coupled receptor 97) (G-protein coupled receptor PGR26) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000182885 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q86Y34 |
| Gene Card | ADGRG3 |
| Uniprot ID | Q86Y34 |
| Pfam | PF00002; PF01825 |
| In ASD | no |
| Allosteric Prediction | no (-0.234488589) |
| Ortholog in Animals | Alpaca_ ADGRG3 ( ortholog_one2one ) Dog_ ADGRG3 ( ortholog_one2one ) GuineaPig_ ADGRG3 ( ortholog_one2one ) Macaque_ ADGRG3 ( ortholog_one2one ) Mouse_ Adgrg3 ( ortholog_one2one ) Pig_ ADGRG3 ( ortholog_one2one ) Rat_ Adgrg3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADGRE3, ADGRL2, VIPR1, ADGRL4, ADGRE2, ADGRG4, ADGRD1, ADGRL3, GHRHR, PTH2R, ADGRE1, ADGRD2, ADGRL1, ADGRB3, EVA1C, ADGRG1, SCTR, ADGRF5, ADGRA3, GLP2R, PTH1R, CALCR, ADGRF3, GIPR, ADGRA1, ADGRF1, ADCYAP1R1, ADGRG5, ADGRE5, CRHR2, ADGRB2, ADGRG6, GCGR, ADGRB1, ADGRG2, ADGRA2, ADGRF4, VIPR2, ADGRG7, CALCRL, CRHR1, GLP1R |
| Tissue | bone.marrow, lymph.node, spleen, whole.blood |
| Tissue Specificity | Expressed in cultured primary dermal lymphatic endothelial cells. {ECO:0000269|PubMed:24178298}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7D76 (EM 3.10A ) 7D77 (EM 2.90A ) |
| DBSNP | rs2290178 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22575658}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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