| Gene Information | |
|---|---|
| Gene Name | ADD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 737 |
| Protein Names | Alpha-adducin (Erythrocyte adducin subunit alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000087274 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P35611 |
| Gene Card | ADD1 |
| Uniprot ID | P35611 |
| Pfam | PF00596 |
| In ASD | no |
| Allosteric Prediction | no (-0.295195207) |
| Ortholog in Animals | Alpaca_ ADD1 ( ortholog_one2one ) Dog_ ADD1 ( ortholog_one2one ) GuineaPig_ ADD1 ( ortholog_one2one ) Macaque_ ADD1 ( ortholog_one2one ) Mouse_ Add1 ( ortholog_one2one ) Pig_ ADD1 ( ortholog_one2one ) Rat_ Add1 ( ortholog_one2one ) Rabbit_ ADD1 ( ortholog_one2one ) |
| Ohnologs | ADD3, ADD2 |
| Paralogs | ADD2, ADD3 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2295497 rs4971 rs4972 rs4961 rs4962 rs4963 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| Mouse PG classification | LPG |
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