| Gene Information | |
|---|---|
| Gene Name | ADCYAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 176 |
| Protein Names | Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] |
| Target Name | pituitary adenylate cyclase-activating polypeptide |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000141433 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P18509 |
| Gene Card | ADCYAP1 |
| Uniprot ID | P18509 |
| Pfam | PF00123 |
| In ASD | no |
| Allosteric Prediction | yes (0.934786619) |
| Ortholog in Animals | Alpaca_ ADCYAP1 ( ortholog_one2one ) Dog_ ADCYAP1 ( ortholog_one2one ) GuineaPig_ ADCYAP1 ( ortholog_one2one ) Macaque_ ADCYAP1 ( ortholog_one2one ) Mouse_ Adcyap1 ( ortholog_one2one ) Pig_ ADCYAP1 ( ortholog_one2one ) Rat_ Adcyap1 ( ortholog_one2one ) Rabbit_ ADCYAP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GHRH, VIP |
| Tissue | brain, pancreas |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.077111(Chimpanzee);0.001000(Mouse);0.001823(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GEA (NMR - ) 2D2P (NMR - ) 2JOD (NMR - ) 6LPB (EM 3.90A ) 6M1I (EM 3.50A ) 6P9Y (EM 3.01A ) 6VN7 (EM 3.20A ) 7VQX (EM 2.74A ) 7WBJ (EM 3.42A ) |
| DBSNP | rs2856966 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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