| Gene Information | |
|---|---|
| Gene Name | ADAMTSL5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | ADAMTS-like protein 5 (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185761 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6ZMM2 |
| Gene Card | ADAMTSL5 |
| Uniprot ID | Q6ZMM2 |
| Pfam | PF19236; PF05986; PF01759; PF00090 |
| In ASD | no |
| Allosteric Prediction | no (-0.995719687) |
| Ortholog in Animals | Alpaca_ ADAMTSL5 ( ortholog_one2one ) GuineaPig_ ADAMTSL5 ( ortholog_one2one ) Macaque_ ADAMTSL5 ( ortholog_one2one ) Mouse_ Adamtsl5 ( ortholog_one2one ) Pig_ ADAMTSL5 ( ortholog_one2one ) Rat_ Adamtsl5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADAMTS5, ADAMTSL2, ADAMTS15, ADAMTS4, ADAMTS1, ADAMTS19, ADAMTS8, ADAMTSL3, ADAMTS7, THSD4, ADAMTSL4, ADAMTS3, ADAMTS20, ADAMTS6, ADAMTS9, ADAMTS12, ADAMTS14, ADAMTS13, ADAMTSL1, ADAMTS10, ADAMTS16, ADAMTS17, PAPLN, ADAMTS2, ADAMTS18 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:23010571}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:23010571}. Note=Colocalized with fibrillin microfibrils. Predominantly distributed in baso-lateral regions of fibroblast extracellular matrix. |
| Mouse PG classification | NA |
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