Gene Information
Gene NameOGFOD1
OrganismHomo sapiens (Human)
Gene Length542
Protein NamesProlyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase)
Target Name2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1
Target TypeNA
Gene Age1488 ( ENSG00000087263 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ8N543
Gene CardOGFOD1
Uniprot IDQ8N543
PfamPF13661; PF10637
In ASDno
Allosteric Predictionyes (0.29220366)
Ortholog in AnimalsAlpaca_ OGFOD1 ( ortholog_one2one )
Dog_ OGFOD1 ( ortholog_one2one )
GuineaPig_ OGFOD1 ( ortholog_one2one )
Macaque_ OGFOD1 ( ortholog_one2one )
Mouse_ Ogfod1 ( ortholog_one2one )
Pig_ OGFOD1 ( ortholog_one2one )
Rat_ Ogfod1 ( ortholog_one2one )
Rabbit_ OGFOD1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4NHX  (X-ray  2.10A  4NHY  (X-ray  2.60A 
DBSNP rs34883368 
Subcellular location [CC][Isoform 1]: Cytoplasm. Nucleus. Note=Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.;
[Isoform 2]: Cytoplasm.
Mouse PG classificationNA
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