| Gene Information | |
|---|---|
| Gene Name | FPGS |
| Organism | Homo sapiens (Human) |
| Gene Length | 587 |
| Protein Names | Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase) |
| Target Name | folylpolyglutamate synthase, mitochondrial |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000136877 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q05932 |
| Gene Card | FPGS |
| Uniprot ID | Q05932 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.376975129) |
| Ortholog in Animals | Alpaca_ FPGS ( ortholog_one2one ) Dog_ FPGS ( ortholog_one2one ) GuineaPig_ FPGS ( ortholog_one2one ) Macaque_ FPGS ( ortholog_one2one ) Mouse_ Fpgs ( ortholog_one2one ) Pig_ FPGS ( ortholog_one2one ) Rat_ Fpgs ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs759336102 rs10760502 rs12686275 rs35789560 rs17855900 rs200314440 rs34354111 |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion inner membrane {ECO:0000269|PubMed:16169100}. Mitochondrion matrix {ECO:0000269|PubMed:16169100, ECO:0000269|PubMed:8408020, ECO:0000269|PubMed:8662720}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:8662720}. |
| Mouse PG classification | NA |
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