| Gene Information | |
|---|---|
| Gene Name | ADAMDEC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 470 |
| Protein Names | ADAM DEC1 (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin-1) (ADAM-like protein decysin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000134028 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O15204 |
| Gene Card | ADAMDEC1 |
| Uniprot ID | O15204 |
| Pfam | PF01562; PF01421 |
| In ASD | no |
| Allosteric Prediction | no (-1.399764332) |
| Ortholog in Animals | Alpaca_ ADAMDEC1 ( ortholog_one2one ) Dog_ ADAMDEC1 ( ortholog_one2one ) GuineaPig_ ADAMDEC1 ( ortholog_one2one ) Macaque_ ADAMDEC1 ( ortholog_one2one ) Mouse_ Adamdec1 ( ortholog_one2one ) Pig_ ADAMDEC1 ( ortholog_one2one ) Rat_ Adamdec1 ( ortholog_one2one ) Rabbit_ ADAMDEC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADAM20, ADAM33, ADAM19, ADAM17, ADAM9, ADAM28, ADAM32, ADAM21, ADAM22, ADAM2, ADAM10, ADAM15, ADAM29, ADAM7, ADAM23, ADAM18, ADAM30, ADAM12, ADAM8, ADAM11 |
| Tissue | lung, sigmoid.colon, spleen, small.intestine.Peyers.patch |
| Tissue Specificity | Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC. {ECO:0000269|PubMed:14632642, ECO:0000269|PubMed:9271581}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7007084 rs3765124 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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