| Gene Information | |
|---|---|
| Gene Name | ADAM23 |
| Organism | Homo sapiens (Human) |
| Gene Length | 832 |
| Protein Names | Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000114948 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75077 |
| Gene Card | ADAM23 |
| Uniprot ID | O75077 |
| Pfam | PF08516; PF00200; PF01562; PF01421 |
| In ASD | no |
| Allosteric Prediction | no (-0.475871337) |
| Ortholog in Animals | Alpaca_ ADAM23 ( ortholog_one2one ) Dog_ ADAM23 ( ortholog_one2one ) GuineaPig_ ADAM23 ( ortholog_one2one ) Macaque_ ADAM23 ( ortholog_one2one ) Mouse_ Adam23 ( ortholog_one2one ) Pig_ ADAM23 ( ortholog_one2one ) Rat_ Adam23 ( ortholog_one2one ) Rabbit_ ADAM23 ( ortholog_one2one ) |
| Ohnologs | ADAM22, ADAM28, ADAM7, ADAM11, ADAM2, ADAM9, ADAM18, ADAM32 |
| Paralogs | ADAM20, ADAM33, ADAM19, ADAM17, ADAM9, ADAM28, ADAM32, ADAM21, ADAM22, ADAM2, ADAM10, ADAM15, ADAM29, ADAM7, ADAM18, ADAMDEC1, ADAM30, ADAM12, ADAM8, ADAM11 |
| Tissue | cerebral.cortex, heart, ovary |
| Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. {ECO:0000269|PubMed:14697522}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform Gamma]: Secreted. |
| Mouse PG classification | NA |
| click here to return to the previous page | |