| Gene Information | |
|---|---|
| Gene Name | FSHR |
| Organism | Homo sapiens (Human) |
| Gene Length | 695 |
| Protein Names | Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) |
| Target Name | follicle-stimulating hormone receptor |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000170820 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P23945 |
| Gene Card | FSHR |
| Uniprot ID | P23945 |
| Pfam | PF00001; PF12369; PF13306; PF01462 |
| In ASD | yes |
| Allosteric Prediction | yes (1.364119931) |
| Ortholog in Animals | Alpaca_ FSHR ( ortholog_one2one ) Dog_ FSHR ( ortholog_one2one ) GuineaPig_ FSHR ( ortholog_one2one ) Macaque_ FSHR ( ortholog_one2one ) Mouse_ Fshr ( ortholog_one2one ) Pig_ FSHR ( ortholog_one2one ) Rat_ Fshr ( ortholog_one2one ) Rabbit_ FSHR ( ortholog_one2one ) |
| Ohnologs | TSHR |
| Paralogs | TSHR, LHCGR |
| Tissue | NA |
| Tissue Specificity | Sertoli cells and ovarian granulosa cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1XWD (X-ray 2.92A ) 4AY9 (X-ray 2.50A ) 4MQW (X-ray 2.90A ) |
| DBSNP | rs121909665 rs6165 rs28928870 rs6167 rs28928871 rs6166 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11847099, ECO:0000269|PubMed:24692546}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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