| Gene Information | |
|---|---|
| Gene Name | ACVR1C |
| Organism | Homo sapiens (Human) |
| Gene Length | 493 |
| Protein Names | Activin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000123612 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NER5 |
| Gene Card | ACVR1C |
| Uniprot ID | Q8NER5 |
| Pfam | PF01064; PF07714; PF08515 |
| In ASD | no |
| Allosteric Prediction | yes (0.060189466) |
| Ortholog in Animals | Alpaca_ ACVR1C ( ortholog_one2one ) Dog_ ACVR1C ( ortholog_one2one ) GuineaPig_ ACVR1C ( ortholog_one2one ) Macaque_ ACVR1C ( ortholog_one2one ) Mouse_ Acvr1c ( ortholog_one2one ) Pig_ ACVR1C ( ortholog_one2one ) Rat_ Acvr1c ( ortholog_one2one ) Rabbit_ ACVR1C ( ortholog_one2one ) |
| Ohnologs | TGFBR1, ACVR1B |
| Paralogs | ACVR1, BMPR2, ACVR2A, TGFBR2, ACVR2B, TGFBR1, BMPR1A, AMHR2, ACVR1B, BMPR1B, ACVRL1 |
| Tissue | adipose.tissue, small.intestine |
| Tissue Specificity | Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy. {ECO:0000269|PubMed:12063393, ECO:0000269|PubMed:12606401}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs56188432 rs34742924 rs35500979 rs7594480 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:12606401}; Single-pass type I membrane protein {ECO:0000269|PubMed:12606401}. |
| Mouse PG classification | NA |
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