| Gene Information | |
|---|---|
| Gene Name | ACTRT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 376 |
| Protein Names | Actin-related protein T1 (ARP-T1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000123165 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TDG2 |
| Gene Card | ACTRT1 |
| Uniprot ID | Q8TDG2 |
| Pfam | PF00022 |
| In ASD | no |
| Allosteric Prediction | no (-0.744052679) |
| Ortholog in Animals | Alpaca_ ACTRT1 ( ortholog_one2one ) GuineaPig_ ACTRT1 ( ortholog_one2one ) Macaque_ ACTRT1 ( ortholog_one2one ) Mouse_ Actrt1 ( ortholog_one2one ) Pig_ ACTRT1 ( ortholog_one2one ) Rat_ Actrt1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | NA |
| Tissue Specificity | In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen. {ECO:0000269|PubMed:28869610}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305|PubMed:28869610}. Cytoplasm {ECO:0000269|PubMed:28869610}. Nucleus {ECO:0000269|PubMed:28869610}. Note=Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway. {ECO:0000269|PubMed:28869610}. |
| Mouse PG classification | NA |
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