| Gene Information | |
|---|---|
| Gene Name | ACTR8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 624 |
| Protein Names | Actin-related protein 8 (hArp8) (INO80 complex subunit N) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000113812 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H981 |
| Gene Card | ACTR8 |
| Uniprot ID | Q9H981 |
| Pfam | PF00022 |
| In ASD | yes |
| Allosteric Prediction | no (-0.791114352) |
| Ortholog in Animals | Alpaca_ ACTR8 ( ortholog_one2one ) Dog_ ACTR8 ( ortholog_one2one ) GuineaPig_ ACTR8 ( ortholog_one2one ) Macaque_ ACTR8 ( ortholog_one2many ) Mouse_ Actr8 ( ortholog_one2one ) Pig_ ACTR8 ( ortholog_one2one ) Rat_ Actr8 ( ortholog_one2one ) Rabbit_ ACTR8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.778946(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4FO0 (X-ray 2.60A ) |
| DBSNP | rs3733082 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18163988}. Chromosome {ECO:0000269|PubMed:18163988}. Note=Specifically localizes to mitotic chromosomes. |
| Mouse PG classification | NA |
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