| Gene Information | |
|---|---|
| Gene Name | SLC52A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | Solute carrier family 52, riboflavin transporter, member 2 (Porcine endogenous retrovirus A receptor 1) (PERV-A receptor 1) (Protein GPR172A) (Riboflavin transporter 3) (hRFT3) |
| Target Name | gamma-hydroxybutyrate (ghb) receptor |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000185803 ) 3 ( ENSG00000285112 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9HAB3 |
| Gene Card | SLC52A2 |
| Uniprot ID | Q9HAB3 |
| Pfam | PF06237 |
| In ASD | no |
| Allosteric Prediction | no (-0.297814253) |
| Ortholog in Animals | Alpaca_ SLC52A2 ( ortholog_one2many ) Macaque_ SLC52A2 ( ortholog_one2one ) Mouse_ Slc52a2 ( ortholog_one2many ) Rat_ Slc52a2 ( ortholog_one2many ) |
| Ohnologs | SLC52A3, SLC52A1 |
| Paralogs | SLC52A1, SLC52A3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, fetal brain and salivary gland. Weakly expressed in other tissues. {ECO:0000269|PubMed:12740431, ECO:0000269|PubMed:20463145}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs797045199 rs397514657 rs397514538 rs377740960 rs398123067 rs398123068 rs398124641 rs754320812 rs148234606 rs397514658 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17197387, ECO:0000269|PubMed:20463145, ECO:0000269|PubMed:24253200, ECO:0000269|PubMed:27702554}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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