| Gene Information | |
|---|---|
| Gene Name | VRK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 474 |
| Protein Names | Inactive serine/threonine-protein kinase VRK3 (Serine/threonine-protein pseudokinase VRK3) (Vaccinia-related kinase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000105053 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IV63 |
| Gene Card | VRK3 |
| Uniprot ID | Q8IV63 |
| Pfam | PF00069; PF13240 |
| In ASD | no |
| Allosteric Prediction | yes (0.354130791) |
| Ortholog in Animals | Alpaca_ VRK3 ( ortholog_one2one ) Dog_ VRK3 ( ortholog_one2one ) GuineaPig_ VRK3 ( ortholog_one2one ) Macaque_ VRK3 ( ortholog_one2one ) Mouse_ Vrk3 ( ortholog_one2one ) Pig_ VRK3 ( ortholog_one2one ) Rat_ Vrk3 ( ortholog_one2one ) Rabbit_ VRK3 ( ortholog_one2one ) |
| Ohnologs | VRK2 |
| Paralogs | CSNK1G3, TTBK2, CSNK1A1L, VRK1, CSNK1G1, CSNK1A1, CDC7, CSNK1G2, CSNK1E, CSNK1D, VRK2, TTBK1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JII (X-ray 2.00A ) |
| DBSNP | rs2033262 rs11547882 rs11547881 rs11547883 rs11879620 rs10410075 rs10409482 rs35261919 rs35331034 rs56407496 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14645249}. |
| Mouse PG classification | NA |
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