| Gene Information | |
|---|---|
| Gene Name | ABCC10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1492 |
| Protein Names | ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000124574 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5T3U5 |
| Gene Card | ABCC10 |
| Uniprot ID | Q5T3U5 |
| Pfam | PF00664; PF00005 |
| In ASD | no |
| Allosteric Prediction | yes (0.270504182) |
| Ortholog in Animals | Alpaca_ ABCC10 ( ortholog_one2one ) Dog_ ABCC10 ( ortholog_one2one ) GuineaPig_ ABCC10 ( ortholog_one2one ) Macaque_ ABCC10 ( ortholog_one2one ) Mouse_ Abcc10 ( ortholog_one2one ) Pig_ ABCC10 ( ortholog_one2one ) Rat_ Abcc10 ( ortholog_one2one ) Rabbit_ ABCC10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABCC1, ABCC8, ABCC3, ABCC9, ABCC5, ABCC6, ABCC4, ABCC12, CFTR, ABCC2, ABCC11 |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Specifically expressed in spleen. {ECO:0000269|PubMed:12566991}.; [Isoform 2]: Widely expressed. {ECO:0000269|PubMed:12566991}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2125739 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}. Basolateral cell membrane {ECO:0000269|PubMed:23087055}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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