| Gene Information | |
|---|---|
| Gene Name | ACSL6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 697 |
| Protein Names | Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 6) (LACS 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000164398 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UKU0 |
| Gene Card | ACSL6 |
| Uniprot ID | Q9UKU0 |
| Pfam | PF00501; PF13193 |
| In ASD | no |
| Allosteric Prediction | no (-0.175915071) |
| Ortholog in Animals | Alpaca_ ACSL6 ( ortholog_one2one ) Dog_ ACSL6 ( ortholog_one2one ) GuineaPig_ ACSL6 ( ortholog_one2one ) Macaque_ ACSL6 ( ortholog_one2one ) Mouse_ Acsl6 ( ortholog_one2one ) Pig_ ACSL6 ( ortholog_one2one ) Rat_ Acsl6 ( ortholog_one2one ) Rabbit_ ACSL6 ( ortholog_one2one ) |
| Ohnologs | ACSL5, ACSL1 |
| Paralogs | SLC27A4, ACSBG1, ACSL1, ACSL3, SLC27A3, ACSBG2, SLC27A6, ACSL4, ACSL5, SLC27A2, SLC27A1, SLC27A5 |
| Tissue | cerebral.cortex, testis |
| Tissue Specificity | Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain. {ECO:0000269|PubMed:10548543}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24269233}; Single-pass type III membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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