| Gene Information | |
|---|---|
| Gene Name | FFAR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 330 |
| Protein Names | Free fatty acid receptor 2 (G-protein coupled receptor 43) |
| Target Name | free fatty acid receptor 2 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000126262 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O15552 |
| Gene Card | FFAR2 |
| Uniprot ID | O15552 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.931920217) |
| Ortholog in Animals | Alpaca_ FFAR2 ( ortholog_one2one ) Dog_ FFAR2 ( ortholog_one2one ) GuineaPig_ FFAR2 ( ortholog_one2one ) Macaque_ FFAR2 ( ortholog_one2one ) Mouse_ Ffar2 ( ortholog_one2one ) Pig_ FFAR2 ( ortholog_one2one ) Rat_ Ffar2 ( ortholog_one2one ) Rabbit_ FFAR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FFAR3, GPR42, P2RY2, P2RY4, OXGR1, P2RY1, SUCNR1, P2RY6, GPR82, GPR31, FFAR1, HCAR3, HCAR1, HCAR2, OXER1 |
| Tissue | appendix, bone.marrow, spleen, whole.blood |
| Tissue Specificity | Expressed at relatively high levels in peripheral blood leukocytes and, to lesser extent, in spleen. {ECO:0000269|PubMed:12496283, ECO:0000269|PubMed:12684041}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs409093 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18801738}; Multi-pass membrane protein {ECO:0000269|PubMed:18801738}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |