| Gene Information | |
|---|---|
| Gene Name | AMER2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 671 |
| Protein Names | APC membrane recruitment protein 2 (Amer2) (Protein FAM123A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000165566 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N7J2 |
| Gene Card | AMER2 |
| Uniprot ID | Q8N7J2 |
| Pfam | PF09422 |
| In ASD | no |
| Allosteric Prediction | no (-1.285622068) |
| Ortholog in Animals | Alpaca_ AMER2 ( ortholog_one2one ) GuineaPig_ AMER2 ( ortholog_one2one ) Macaque_ AMER2 ( ortholog_one2one ) Mouse_ Amer2 ( ortholog_one2one ) Pig_ AMER2 ( ortholog_one2one ) Rat_ Amer2 ( ortholog_one2one ) Rabbit_ AMER2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AMER1, AMER3 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2282406 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22128170}; Peripheral membrane protein {ECO:0000269|PubMed:22128170}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. |
| Mouse PG classification | NA |
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