Gene Information
Gene NameACP1
OrganismHomo sapiens (Human)
Gene Length158
Protein NamesLow molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1)
Target Namelow molecular weight phosphotyrosine protein phosphatase
Target TypeNA
Gene Age1488 ( ENSG00000143727 )
Evolutionary StageEuk+Bac
AlphaFoldDBP24666
Gene CardACP1
Uniprot IDP24666
PfamPF01451
In ASDno
Allosteric Predictionno (-0.206206797)
Ortholog in AnimalsAlpaca_ ACP1 ( ortholog_one2one )
Macaque_ ACP1 ( ortholog_one2many )
Mouse_ Acp1 ( ortholog_one2one )
Pig_ ACP1 ( ortholog_one2one )
Rat_ AABR07036974.1 ( ortholog_one2one )
OhnologsNA
ParalogsPTRHD1
TissueNA
Tissue Specificity[Isoform 2]: Expressed in T-lymphocytes. {ECO:0000269|PubMed:9038134}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1XWW  (X-ray  1.63A  3N8I  (X-ray  1.50A  4Z99  (X-ray  2.30A  4Z9A  (X-ray  2.10A  4Z9B  (X-ray  2.41A  5JNR  (X-ray  2.00A  5JNS  (X-ray  1.80A  5JNT  (X-ray  1.45A  5KQG  (X-ray  1.50A  5KQL  (X-ray  1.45A  5KQM  (X-ray  1.91A  5KQP  (X-ray  2.05A  5PNT  (X-ray  2.20A  6Y2V  (X-ray  2.00A  6Y2W  (X-ray  1.77A  7KH8  (X-ray  1.30A 
DBSNP rs11691572  rs79716074  rs35569198 
Subcellular location [CC]Cytoplasm.
Mouse PG classificationNA
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