| Gene Information | |
|---|---|
| Gene Name | ACOX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 681 |
| Protein Names | Peroxisomal acyl-coenzyme A oxidase 2 (EC 1.17.99.3) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase) (Trihydroxycoprostanoyl-CoA oxidase) (THCA-CoA oxidase) (THCCox) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000168306 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q99424 |
| Gene Card | ACOX2 |
| Uniprot ID | Q99424 |
| Pfam | PF01756; PF14749 |
| In ASD | no |
| Allosteric Prediction | no (-0.181580401) |
| Ortholog in Animals | Alpaca_ ACOX2 ( ortholog_one2one ) Dog_ ACOX2 ( ortholog_one2one ) GuineaPig_ ACOX2 ( ortholog_one2one ) Macaque_ ACOX2 ( ortholog_one2one ) Mouse_ Acox2 ( ortholog_one2one ) Pig_ ACOX2 ( ortholog_one2one ) Rat_ Acox2 ( ortholog_one2one ) Rabbit_ ACOX2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOX1, ACAD11, ACADM, ACAD9, IVD, GCDH, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACADVL, ACADSB, ACADL |
| Tissue | NA |
| Tissue Specificity | Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. {ECO:0000269|PubMed:8943006}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs150832314 |
| Subcellular location [CC] | Peroxisome {ECO:0000269|PubMed:27884763, ECO:0000269|PubMed:8943006}. |
| Mouse PG classification | NA |
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