| Gene Information | |
|---|---|
| Gene Name | ACOT7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (hBACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000097021 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O00154 |
| Gene Card | ACOT7 |
| Uniprot ID | O00154 |
| Pfam | PF03061 |
| In ASD | no |
| Allosteric Prediction | no (-0.112198704) |
| Ortholog in Animals | Dog_ ACOT7 ( ortholog_one2one ) GuineaPig_ ACOT7 ( ortholog_one2one ) Macaque_ ACOT7 ( ortholog_one2one ) Mouse_ Acot7 ( ortholog_one2one ) Pig_ ACOT7 ( ortholog_one2one ) Rat_ Acot7 ( ortholog_one2one ) Rabbit_ ACOT7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOT12, ACOT11 |
| Tissue | NA |
| Tissue Specificity | Isoform 4 is expressed exclusively in brain. {ECO:0000269|PubMed:12435388}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QQ2 (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 4]: Cytoplasm, cytosol {ECO:0000305|PubMed:12435388}.; [Isoform 6]: Cytoplasm, cytosol {ECO:0000305|PubMed:12435388}.; [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:12435388}.; [Isoform 5]: Mitochondrion {ECO:0000269|PubMed:12435388}. |
| Mouse PG classification | NA |
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