Gene Information
Gene NameACOT6
OrganismHomo sapiens (Human)
Gene Length421
Protein NamesAcyl-coenzyme A thioesterase 6 (Acyl-CoA thioesterase 6) (EC 3.1.2.-)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000205669 )
Evolutionary StageEumetazoa
AlphaFoldDBQ3I5F7
Gene CardACOT6
Uniprot IDQ3I5F7
PfamPF08840; PF04775
In ASDno
Allosteric Predictionno (-1.145711368)
Ortholog in AnimalsAlpaca_ ACOT6 ( ortholog_one2one )
Dog_ ACOT6 ( ortholog_one2one )
GuineaPig_ ACOT6 ( ortholog_one2one )
Mouse_ Acot6 ( ortholog_one2one )
Pig_ ACOT6 ( ortholog_one2one )
Rat_ Acot6 ( ortholog_one2one )
OhnologsNA
ParalogsACOT4, ACOT1, ACOT2, BAAT
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17782052 
Subcellular location [CC][Isoform 1]: Peroxisome {ECO:0000305|PubMed:16940157}. Note=Localization to the peroxisome is uncertain since the potential C-terminal peroxisome targeting signal found in the mouse ortholog is not perfectly conserved. {ECO:0000305|PubMed:16940157}.;
[Isoform 2]: Cytoplasm {ECO:0000305|PubMed:16940157}. Note=Recombinant N-terminally GFP-tagged protein localizes to the cytosol. {ECO:0000305|PubMed:16940157}.
Mouse PG classificationNA
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