| Gene Information | |
|---|---|
| Gene Name | ACOT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 483 |
| Protein Names | Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000119673 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P49753 |
| Gene Card | ACOT2 |
| Uniprot ID | P49753 |
| Pfam | PF08840; PF04775 |
| In ASD | no |
| Allosteric Prediction | no (-0.029458664) |
| Ortholog in Animals | Mouse_ Acot3 ( ortholog_many2many ) Mouse_ Acot1 ( ortholog_many2many ) Mouse_ Acot5 ( ortholog_many2many ) Mouse_ Acot2 ( ortholog_many2many ) Rat_ Acot5 ( ortholog_many2many ) Rat_ Acot3 ( ortholog_many2many ) Rat_ Acot1 ( ortholog_many2many ) Rat_ Acot2 ( ortholog_many2many ) Rat_ AC094055.1 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | ACOT1, ACOT6, ACOT4, BAAT |
| Tissue | zone.of.skin |
| Tissue Specificity | Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas. {ECO:0000269|PubMed:16940157}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3HLK (X-ray 2.10A ) |
| DBSNP | rs11545741 rs7494 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:16940157}. |
| Mouse PG classification | NA |
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