| Gene Information | |
|---|---|
| Gene Name | NTF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 257 |
| Protein Names | Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor) |
| Target Name | neurotrophin-3 |
| Target Type | Discontinued target |
| Gene Age | 645 ( ENSG00000185652 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P20783 |
| Gene Card | NTF3 |
| Uniprot ID | P20783 |
| Pfam | PF00243; PF19338 |
| In ASD | no |
| Allosteric Prediction | yes (0.194150089) |
| Ortholog in Animals | Alpaca_ NTF3 ( ortholog_one2one ) Dog_ NTF3 ( ortholog_one2one ) GuineaPig_ NTF3 ( ortholog_one2one ) Macaque_ NTF3 ( ortholog_one2one ) Mouse_ Ntf3 ( ortholog_one2one ) Pig_ NTF3 ( ortholog_one2one ) Rat_ Ntf3 ( ortholog_one2one ) Rabbit_ NTF3 ( ortholog_one2one ) |
| Ohnologs | NGF, BDNF |
| Paralogs | NGF, NTF4, BDNF |
| Tissue | NA |
| Tissue Specificity | Brain and peripheral tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1B8K (X-ray 2.15A ) 1BND (X-ray 2.30A ) 1NT3 (X-ray 2.40A ) 3BUK (X-ray 2.60A ) |
| DBSNP | rs1805149 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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