| Gene Information | |
|---|---|
| Gene Name | ACOT11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 607 |
| Protein Names | Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000162390 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8WXI4 |
| Gene Card | ACOT11 |
| Uniprot ID | Q8WXI4 |
| Pfam | PF03061; PF01852 |
| In ASD | no |
| Allosteric Prediction | no (-0.884224555) |
| Ortholog in Animals | Alpaca_ ACOT11 ( ortholog_one2one ) Dog_ ACOT11 ( ortholog_one2one ) GuineaPig_ ACOT11 ( ortholog_one2one ) Macaque_ ACOT11 ( ortholog_one2one ) Mouse_ Acot11 ( ortholog_one2one ) Pig_ ACOT11 ( ortholog_one2one ) Rat_ Acot11 ( ortholog_one2one ) Rabbit_ ACOT11 ( ortholog_one2one ) |
| Ohnologs | ACOT12 |
| Paralogs | ACOT12, ACOT7 |
| Tissue | heart, small.intestine |
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3FO5 (X-ray 2.00A ) 6VVQ (X-ray 3.09A ) |
| DBSNP | rs34630746 rs2304306 rs1702003 rs2304305 rs12403630 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:22897136}. Cytoplasm {ECO:0000269|PubMed:22897136}. |
| Mouse PG classification | NA |
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