| Gene Information | |
|---|---|
| Gene Name | ACO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 780 |
| Protein Names | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
| Target Name | aconitate hydratase, mitochondrial |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000100412 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q99798 |
| Gene Card | ACO2 |
| Uniprot ID | Q99798 |
| Pfam | PF00330; PF00694 |
| In ASD | no |
| Allosteric Prediction | yes (0.734384466) |
| Ortholog in Animals | Alpaca_ ACO2 ( ortholog_one2one ) Dog_ ACO2 ( ortholog_one2one ) GuineaPig_ ACO2 ( ortholog_one2one ) Macaque_ ACO2 ( ortholog_one2one ) Mouse_ Aco2 ( ortholog_one2one ) Pig_ ACO2 ( ortholog_one2one ) Rat_ Aco2 ( ortholog_one2one ) Rabbit_ ACO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACO1, IREB2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.036223(Chimpanzee);0.018548(Mouse);0.002432(Rat);0.034783(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs141772938 rs786200924 rs786204828 rs752034900 rs786204829 rs1804785 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:P16276}. |
| Mouse PG classification | NA |
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