| Gene Information | |
|---|---|
| Gene Name | CHST10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 356 |
| Protein Names | Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST) (HuHNK-1ST) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115526 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O43529 |
| Gene Card | CHST10 |
| Uniprot ID | O43529 |
| Pfam | PF03567 |
| In ASD | no |
| Allosteric Prediction | no (-0.757496386) |
| Ortholog in Animals | Alpaca_ CHST10 ( ortholog_one2one ) Dog_ CHST10 ( ortholog_one2one ) GuineaPig_ CHST10 ( ortholog_one2one ) Macaque_ CHST10 ( ortholog_one2one ) Mouse_ Chst10 ( ortholog_one2one ) Pig_ CHST10 ( ortholog_one2one ) Rat_ Chst10 ( ortholog_one2one ) Rabbit_ CHST10 ( ortholog_one2one ) |
| Ohnologs | CHST11, CHST13 |
| Paralogs | CHST11, CHST8, CHST14, CHST12, CHST13, CHST9 |
| Tissue | NA |
| Tissue Specificity | In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe. {ECO:0000269|PubMed:32149355, ECO:0000269|PubMed:9478973}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35177621 rs3748932 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:O54702}; Single-pass type II membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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