| Gene Information | |
|---|---|
| Gene Name | ACER2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 275 |
| Protein Names | Alkaline ceramidase 2 (AlkCDase 2) (Alkaline CDase 2) (haCER2) (EC 3.5.1.-) (EC 3.5.1.23) (Acylsphingosine deacylase 3-like) (N-acylsphingosine amidohydrolase 3-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000177076 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5QJU3 |
| Gene Card | ACER2 |
| Uniprot ID | Q5QJU3 |
| Pfam | PF05875 |
| In ASD | no |
| Allosteric Prediction | no (-0.25135513) |
| Ortholog in Animals | Alpaca_ ACER2 ( ortholog_one2one ) Dog_ ACER2 ( ortholog_one2one ) GuineaPig_ ACER2 ( ortholog_one2one ) Macaque_ ACER2 ( ortholog_one2one ) Mouse_ Acer2 ( ortholog_one2one ) Pig_ ACER2 ( ortholog_one2one ) Rat_ Acer2 ( ortholog_one2one ) Rabbit_ ACER2 ( ortholog_one2one ) |
| Ohnologs | ACER1 |
| Paralogs | ACER1, ACER3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in placenta. {ECO:0000269|PubMed:16940153}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10964136 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:16940153, ECO:0000269|PubMed:20089856}; Multi-pass membrane protein {ECO:0000269|PubMed:20089856}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |