| Gene Information | |
|---|---|
| Gene Name | ACAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 397 |
| Protein Names | Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase) |
| Target Name | acetyl-coa acetyltransferase, cytosolic |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000120437 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9BWD1 |
| Gene Card | ACAT2 |
| Uniprot ID | Q9BWD1 |
| Pfam | PF02803; PF00108 |
| In ASD | no |
| Allosteric Prediction | yes (0.654715853) |
| Ortholog in Animals | Alpaca_ ACAT2 ( ortholog_one2one ) Dog_ ACAT2 ( ortholog_one2one ) GuineaPig_ ACAT2 ( ortholog_one2one ) Mouse_ Acat3 ( ortholog_one2many ) Mouse_ Acat2 ( ortholog_one2many ) Pig_ ACAT2 ( ortholog_one2one ) Rat_ Acat2 ( ortholog_one2many ) Rat_ Acat2l1 ( ortholog_one2many ) Rabbit_ ACAT2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACAT1, ACAA2, ACAA1, HADHB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.013333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WL4 (X-ray 1.55A ) 1WL5 (X-ray 2.26A ) |
| DBSNP | rs25683 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000305|PubMed:7911016}. |
| Mouse PG classification | NA |
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