| Gene Information | |
|---|---|
| Gene Name | IRF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (Multiple myeloma oncogene 1) (NF-EM5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000137265 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15306 |
| Gene Card | IRF4 |
| Uniprot ID | Q15306 |
| Pfam | PF00605; PF10401 |
| In ASD | no |
| Allosteric Prediction | no (-0.461753006) |
| Ortholog in Animals | Alpaca_ IRF4 ( ortholog_one2one ) Dog_ IRF4 ( ortholog_one2one ) GuineaPig_ IRF4 ( ortholog_one2one ) Macaque_ IRF4 ( ortholog_one2one ) Mouse_ Irf4 ( ortholog_one2one ) Pig_ IRF4 ( ortholog_one2one ) Rat_ Irf4 ( ortholog_one2one ) Rabbit_ IRF4 ( ortholog_one2one ) |
| Ohnologs | IRF8, IRF9 |
| Paralogs | IRF7, IRF5, IRF3, IRF6, IRF9, IRF2, IRF8, IRF1 |
| Tissue | adipose.tissue, spleen, ectocervix, endocervix |
| Tissue Specificity | Lymphoid cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DLL (NMR - ) 6TD4 (X-ray 1.71A ) 7JM4 (X-ray 2.95A ) 7O56 (X-ray 2.60A ) 7OGS (X-ray 2.37A ) 7OOT (X-ray 2.25A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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