| Gene Information | |
|---|---|
| Gene Name | ACAD9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 621 |
| Protein Names | Complex I assembly factor ACAD9, mitochondrial (Acyl-CoA dehydrogenase family member 9) (ACAD-9) (EC 1.3.8.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000177646 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H845 |
| Gene Card | ACAD9 |
| Uniprot ID | Q9H845 |
| Pfam | PF00441; PF02770; PF02771 |
| In ASD | no |
| Allosteric Prediction | no (-0.304597266) |
| Ortholog in Animals | Alpaca_ ACAD9 ( ortholog_one2one ) Dog_ ACAD9 ( ortholog_one2one ) Macaque_ ACAD9 ( ortholog_one2one ) Mouse_ Acad9 ( ortholog_one2one ) Pig_ ACAD9 ( ortholog_one2one ) Rat_ Acad9 ( ortholog_one2one ) Rabbit_ ACAD9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOX1, ACAD11, ACADM, IVD, GCDH, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACOX2, ACADVL, ACADSB, ACADL |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in most normal human tissues and cancer cell lines with high level of expression in heart, skeletal muscles, brain, kidney and liver (PubMed:12359260). In the cerebellum uniquely expressed in the granular layer (at protein level) (PubMed:21237683). {ECO:0000269|PubMed:12359260, ECO:0000269|PubMed:21237683}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387907041 rs377547811 rs387907042 rs143383023 rs115532916 rs1447947184 rs149753643 rs777282696 rs368949613 rs139145143 rs4494951 rs781149699 rs377022708 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:16020546, ECO:0000269|PubMed:20816094}; Peripheral membrane protein {ECO:0000269|PubMed:16020546}; Matrix side {ECO:0000269|PubMed:16020546}. Note=Essentially associated with membranes. {ECO:0000269|PubMed:16020546}. |
| Mouse PG classification | NA |
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