| Gene Information | |
|---|---|
| Gene Name | ACAD11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 780 |
| Protein Names | Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.8.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000240303 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q709F0 |
| Gene Card | ACAD11 |
| Uniprot ID | Q709F0 |
| Pfam | PF00441; PF02770; PF02771; PF01636 |
| In ASD | no |
| Allosteric Prediction | no (-1.008175964) |
| Ortholog in Animals | Alpaca_ ACAD11 ( ortholog_one2one ) Dog_ ACAD11 ( ortholog_one2one ) GuineaPig_ ACAD11 ( ortholog_one2one ) Macaque_ ACAD11 ( ortholog_one2one ) Mouse_ Acad11 ( ortholog_one2one ) Pig_ ACAD11 ( ortholog_one2one ) Rat_ Acad11 ( ortholog_one2one ) Rabbit_ ACAD11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOX1, ACADM, ACAD9, IVD, GCDH, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACOX2, ACADVL, ACADSB, ACADL |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in brain followed by liver, heart and kidney. {ECO:0000269|PubMed:21237683}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002865(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2WBI (X-ray 2.80A ) |
| DBSNP | rs6776576 |
| Subcellular location [CC] | Peroxisome {ECO:0000250|UniProtKB:Q80XL6}. Mitochondrion membrane {ECO:0000269|PubMed:21237683}. Note=Has been detected associated with mitochondrial membrane, but no matrix, in kidney and cerebellum, as well as in a neuroblastoma cell line, but not in skin fibroblasts, where it is observed in cytoplasmic vesicles (PubMed:21237683). No mitochondrial targeting signals could be predicted for any known isoform, including a putative isoform starting at Met-316. {ECO:0000269|PubMed:21237683}. |
| Mouse PG classification | NA |
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