| Gene Information | |
|---|---|
| Gene Name | TOE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 510 |
| Protein Names | Target of EGR1 protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000132773 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96GM8 |
| Gene Card | TOE1 |
| Uniprot ID | Q96GM8 |
| Pfam | PF04857; PF00642 |
| In ASD | no |
| Allosteric Prediction | no (-1.105358867) |
| Ortholog in Animals | Alpaca_ TOE1 ( ortholog_one2one ) Dog_ TOE1 ( ortholog_one2one ) GuineaPig_ TOE1 ( ortholog_one2one ) Macaque_ TOE1 ( ortholog_one2one ) Mouse_ Toe1 ( ortholog_one2one ) Pig_ TOE1 ( ortholog_one2one ) Rat_ Toe1 ( ortholog_one2one ) Rabbit_ TOE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PNLDC1, PARN |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:28092684}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FC6 (NMR - ) |
| DBSNP | rs774056037 rs371848318 rs148067486 rs777030573 rs1570621473 rs778263701 rs368182654 rs758153898 rs750266350 rs9429157 rs61323219 rs1570626350 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12562764}. Nucleus speckle {ECO:0000269|PubMed:12562764}. Note=Localizes to nuclear speckles. |
| Mouse PG classification | NA |
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