| Gene Information | |
|---|---|
| Gene Name | CCDC61 |
| Organism | Homo sapiens (Human) |
| Gene Length | 512 |
| Protein Names | Centrosomal protein CCDC61 (Coiled-coil domain-containing protein 61) (VFL3 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000104983 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6R9 |
| Gene Card | CCDC61 |
| Uniprot ID | Q9Y6R9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.632958713) |
| Ortholog in Animals | Alpaca_ CCDC61 ( ortholog_one2one ) Dog_ CCDC61 ( ortholog_one2one ) GuineaPig_ CCDC61 ( ortholog_one2one ) Macaque_ CCDC61 ( ortholog_one2one ) Mouse_ Ccdc61 ( ortholog_one2one ) Pig_ CCDC61 ( ortholog_one2one ) Rat_ Ccdc61 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPTY2D1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6HXT (X-ray 2.55A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30354798, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:30354798, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:32375023}. Note=Localization at the centriolar satellite is dependent on intact microtubule network (PubMed:30354798). Localizes at the centriole subdistal appendages and proximal ends (PubMed:31789463). Localized to centrosomal/satellite-like structures with the onset of centrosome separation in early G2 (PubMed:30354798). {ECO:0000269|PubMed:30354798, ECO:0000269|PubMed:31789463}. |
| Mouse PG classification | NA |
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