| Gene Information | |
|---|---|
| Gene Name | ACAA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 397 |
| Protein Names | 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1) |
| Target Name | 3-ketoacyl-coa thiolase, mitochondrial |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000167315 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P42765 |
| Gene Card | ACAA2 |
| Uniprot ID | P42765 |
| Pfam | PF02803; PF00108 |
| In ASD | no |
| Allosteric Prediction | no (-0.250250438) |
| Ortholog in Animals | Alpaca_ ACAA2 ( ortholog_one2one ) Dog_ ACAA2 ( ortholog_one2one ) GuineaPig_ ACAA2 ( ortholog_one2one ) Macaque_ ACAA2 ( ortholog_one2one ) Mouse_ Acaa2 ( ortholog_one2one ) Pig_ ACAA2 ( ortholog_one2one ) Rat_ Acaa2 ( ortholog_one2one ) Rabbit_ ACAA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACAT2, ACAT1, ACAA1, HADHB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4C2J (X-ray 2.00A ) 4C2K (X-ray 2.00A ) |
| DBSNP | rs11549285 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:18371312}. |
| Mouse PG classification | NA |
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