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Gene Information
Gene Name
ABO
Organism
Homo sapiens (Human)
Gene Length
354
Protein Names
Histo-blood group ABO system transferase (Fucosylglycoprotein 3-alpha-galactosyltransferase) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase) (EC 2.4.1.40) (Glycoprotein-fucosylgalactoside alpha-galactosyltransferase) (EC 2.4.1.37) (Histo-blood group A transferase) (A transferase) (Histo-blood group B transferase) (B transferase) (NAGAT) [Cleaved into: Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form]
Target Name
histo-blood group abo system transferase
Target Type
NA
Gene Age
382 ( ENSG00000175164 )
3 ( ENSG00000281879 )
Evolutionary Stage
Vertebrata
AlphaFoldDB
P16442
Gene Card
ABO
Uniprot ID
P16442
Pfam
PF03414
In ASD
no
Allosteric Prediction
no (-0.047816795)
Ortholog in Animals
Dog_ ABO ( ortholog_one2one )
Macaque_ ABO ( ortholog_one2one )
Mouse_ Abo ( ortholog_one2one )
Rat_ Abo3 ( ortholog_one2many )
Rat_ Abo ( ortholog_one2many )
Ohnologs
NA
Paralogs
GBGT1, A3GALT2, GLT6D1
Tissue
NA
Tissue Specificity
NA
Pharmacological Animal Models
NA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1LZ0
(X-ray
1.80A
)
1LZ7
(X-ray
1.65A
)
1LZI
(X-ray
1.35A
)
1LZJ
(X-ray
1.32A
)
1R7T
(X-ray
2.09A
)
1R7U
(X-ray
1.61A
)
1R7V
(X-ray
2.09A
)
1R7X
(X-ray
1.97A
)
1R7Y
(X-ray
1.75A
)
1R80
(X-ray
1.65A
)
1R81
(X-ray
1.75A
)
1R82
(X-ray
1.55A
)
1WSZ
(X-ray
1.59A
)
1WT0
(X-ray
1.80A
)
1WT1
(X-ray
1.55A
)
1WT2
(X-ray
1.90A
)
1WT3
(X-ray
1.80A
)
1XZ6
(X-ray
1.55A
)
1ZHJ
(X-ray
1.59A
)
1ZI1
(X-ray
1.57A
)
1ZI3
(X-ray
1.69A
)
1ZI4
(X-ray
1.85A
)
1ZI5
(X-ray
1.55A
)
1ZIZ
(X-ray
1.49A
)
1ZJ0
(X-ray
1.67A
)
1ZJ1
(X-ray
1.65A
)
1ZJ2
(X-ray
1.69A
)
1ZJ3
(X-ray
1.69A
)
1ZJO
(X-ray
1.64A
)
1ZJP
(X-ray
1.59A
)
2A8U
(X-ray
1.69A
)
2A8W
(X-ray
1.59A
)
2I7B
(X-ray
1.99A
)
2O1F
(X-ray
1.99A
)
2O1G
(X-ray
1.71A
)
2O1H
(X-ray
1.67A
)
2PGV
(X-ray
1.79A
)
2PGY
(X-ray
2.39A
)
2RIT
(X-ray
1.43A
)
2RIX
(X-ray
1.75A
)
2RIY
(X-ray
1.55A
)
2RIZ
(X-ray
1.45A
)
2RJ0
(X-ray
1.52A
)
2RJ1
(X-ray
1.55A
)
2RJ4
(X-ray
1.47A
)
2RJ5
(X-ray
1.45A
)
2RJ6
(X-ray
1.41A
)
2RJ7
(X-ray
1.70A
)
2RJ8
(X-ray
1.69A
)
2RJ9
(X-ray
1.69A
)
2Y7A
(X-ray
2.06A
)
3I0C
(X-ray
1.55A
)
3I0D
(X-ray
1.90A
)
3I0E
(X-ray
1.81A
)
3I0F
(X-ray
1.56A
)
3I0G
(X-ray
1.40A
)
3I0H
(X-ray
2.00A
)
3I0I
(X-ray
1.90A
)
3I0J
(X-ray
1.48A
)
3I0K
(X-ray
2.20A
)
3I0L
(X-ray
1.60A
)
3IOH
(X-ray
1.25A
)
3IOI
(X-ray
1.45A
)
3IOJ
(X-ray
1.65A
)
3SX3
(X-ray
1.45A
)
3SX5
(X-ray
1.43A
)
3SX7
(X-ray
1.42A
)
3SX8
(X-ray
1.47A
)
3SXA
(X-ray
1.50A
)
3SXB
(X-ray
1.49A
)
3SXC
(X-ray
1.90A
)
3SXD
(X-ray
1.55A
)
3SXE
(X-ray
1.49A
)
3SXG
(X-ray
1.86A
)
3U0X
(X-ray
1.85A
)
3U0Y
(X-ray
1.60A
)
3V0L
(X-ray
1.75A
)
3V0M
(X-ray
1.68A
)
3V0N
(X-ray
1.75A
)
3V0O
(X-ray
1.65A
)
3V0P
(X-ray
1.90A
)
3V0Q
(X-ray
1.80A
)
3ZGF
(X-ray
1.70A
)
3ZGG
(X-ray
1.90A
)
4C2S
(X-ray
2.48A
)
4FQW
(X-ray
2.02A
)
4FRA
(X-ray
1.43A
)
4FRB
(X-ray
1.54A
)
4FRD
(X-ray
1.55A
)
4FRE
(X-ray
1.85A
)
4FRH
(X-ray
1.80A
)
4FRL
(X-ray
1.90A
)
4FRM
(X-ray
1.90A
)
4FRO
(X-ray
1.75A
)
4FRP
(X-ray
2.00A
)
4FRQ
(X-ray
2.35A
)
4GBP
(X-ray
2.15A
)
4KC1
(X-ray
1.50A
)
4KC2
(X-ray
1.70A
)
4KC4
(X-ray
1.60A
)
4KXO
(X-ray
2.00A
)
4Y62
(X-ray
1.60A
)
4Y63
(X-ray
1.30A
)
4Y64
(X-ray
1.60A
)
5BXC
(X-ray
1.40A
)
5C1G
(X-ray
1.46A
)
5C1H
(X-ray
1.55A
)
5C1L
(X-ray
1.40A
)
5C36
(X-ray
1.55A
)
5C38
(X-ray
1.45A
)
5C3A
(X-ray
1.33A
)
5C3B
(X-ray
1.40A
)
5C3D
(X-ray
1.39A
)
5C47
(X-ray
1.39A
)
5C48
(X-ray
1.46A
)
5C49
(X-ray
1.49A
)
5C4B
(X-ray
1.54A
)
5C4C
(X-ray
1.43A
)
5C4D
(X-ray
1.40A
)
5C4E
(X-ray
1.55A
)
5C4F
(X-ray
1.41A
)
5C8R
(X-ray
1.45A
)
5CMF
(X-ray
1.95A
)
5CMG
(X-ray
1.83A
)
5CMH
(X-ray
1.61A
)
5CMI
(X-ray
1.85A
)
5CMJ
(X-ray
1.73A
)
5CQL
(X-ray
1.69A
)
5CQM
(X-ray
1.65A
)
5CQN
(X-ray
1.61A
)
5CQO
(X-ray
1.69A
)
5CQP
(X-ray
1.83A
)
5M79
(X-ray
1.30A
)
5M7A
(X-ray
1.30A
)
5M7B
(X-ray
1.50A
)
5M7C
(X-ray
1.60A
)
5M7D
(X-ray
1.20A
)
5TJK
(X-ray
1.45A
)
5TJL
(X-ray
1.89A
)
5TJN
(X-ray
1.47A
)
5TJO
(X-ray
1.57A
)
6BJI
(X-ray
1.54A
)
6BJJ
(X-ray
1.45A
)
6BJK
(X-ray
2.12A
)
6BJL
(X-ray
1.69A
)
6BJM
(X-ray
1.45A
)
6GWY
(X-ray
1.40A
)
6GWZ
(X-ray
1.65A
)
6GX0
(X-ray
1.25A
)
6GX1
(X-ray
1.60A
)
6GX2
(X-ray
1.07A
)
DBSNP
rs8176696
rs688976
rs549446
rs512770
rs1053878
rs8176738
rs55756402
rs7853989
rs8176739
rs8176740
rs8176743
rs8176745
rs8176746
rs8176747
rs41302905
rs8176748
Subcellular location [CC]
Golgi apparatus, Golgi stack membrane;
Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Mouse PG classification
NA
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