| Gene Information | |
|---|---|
| Gene Name | ABI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | ABI gene family member 3 (New molecule including SH3) (Nesh) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000108798 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P2A4 |
| Gene Card | ABI3 |
| Uniprot ID | Q9P2A4 |
| Pfam | PF07815; PF14604 |
| In ASD | no |
| Allosteric Prediction | no (-1.331874797) |
| Ortholog in Animals | Alpaca_ ABI3 ( ortholog_one2one ) Dog_ ABI3 ( ortholog_one2one ) Macaque_ ABI3 ( ortholog_one2one ) Mouse_ Abi3 ( ortholog_one2one ) Rat_ Abi3 ( ortholog_one2one ) Rabbit_ ABI3 ( ortholog_one2one ) |
| Ohnologs | ABI1, ABI2 |
| Paralogs | ABI2, ABI1 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle. {ECO:0000269|PubMed:10978530}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2233369 rs616338 rs616338 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11956071}. Note=Colocalizes with PAK2 at leading edge of cells. |
| Mouse PG classification | NA |
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